By Kenneth Miles, C. Charnsangavej, C. Cuenod
This new text-atlas makes a speciality of anatomy and procedural technique for perfusion CT imaging within the prognosis and administration of melanoma. it's going to use a mixture of images and schematic diagrams that convey how this new modality can be utilized to evaluate anatomy and advisor healing interventions. It starts with an introductory part discussing the cutting-edge and heritage aid (including software program) within the use of the approach; there then follows a series of chapters that evaluation functions for every of the most physique structures and anatomic areas. The ebook concludes with a bit at the makes use of of perfusion CT in tracking medical trials, and in addition experiences new purposes for mixed modalities corresponding to CT/PET.
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Additional info for Multi-Detector Computed Tomography in Oncology: CT Perfusion Imaging
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10). The variability in CT blood flow and blood volume measurements in the repeated studies was 13% and 7%, respectively. 4 cm in diameter. 49 The ex vivo method of radioactive microspheres was used to validate the CT blood flow measurements. The precision of the CT technique for the measurement of BF, PS, BV, and MTT was determined by repeating the scan three times in four of the nine rabbits under steadystate conditions. 0001). The precision of blood flow, capillary permeability surface area product, 9781842143094-Ch02 8/8/07 11:54 AM Page 41 Scientific basis and validation 41 blood volume, and mean transit time was 14%, 18%, 20% and 24%, respectively.
Quantitative measurements of capillary transport in human brain tumours by computed tomography. Ann Neurol 1991; 30: 581–8. 19. Miles KA, Hayball M, Dixon AK. Colour perfusion imaging: a new application of computed tomography. Lancet 1991; 337: 643–5. 20. Miles KA, Hayball MP, Dixon AK. Functional images of hepatic perfusion obtained with dynamic computed tomography. Radiology 1993; 188: 405–11. 9781842143094-Ch01 8/8/07 4:26 PM Page 14 9781842143094-Ch02 8/8/07 11:54 AM Page 15 2 Scientific basis and validation Ting-Yim Lee and Errol Stewart INTRODUCTION In this chapter, the theory of computed tomography (CT) tumor perfusion measurement will be discussed.
Tissue mean transit time from dynamic computed tomography by a simple deconvolution technique. Invest Radiol 1983; 18: 94–9. 3. Miles KA. Measurement of tissue perfusion by dynamic computed tomography. Br J Radiol 1991; 64: 409–12. 4. Blomley MJK, Coulden R, Bufkin CRT et al. Contrast bolus dynamic computed tomography for the measurement of solid organ perfusion. Invest Radiol 1993; 28 (Suppl 5): S72–7. 5. Blomley MJK, Dawson P. Bolus dynamics: theoretical and experimental aspects. Br J Radiol 1997; 70: 351–9.