By Robert J. Amdur, Ernest L. Mazzaferri
This quantity outlines sufferer care from analysis via numerous remedies for thyroid melanoma sufferers. It serves as a cutting-edge reference for clinicians offering finished info at the scope of this sickness, together with surgical procedure, nuclear medication remedies, recurrence and metastases. Reference details is integrated for either physicians and thyroid melanoma sufferers.
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Additional info for Essentials of Thyroid Cancer Management
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POORLY DIFFERENTIATED THYROID CANCER (INSULAR CARCINOMA) These tumors are derived from follicular epithelial cells and are intermediate between differentiated and undifferentiated (anaplastic) thyroid carcinomas both histologically and in terms of biologic behavior. Most poorly differentiated thyroid carcinomas are widely invasive and may show extension beyond the thyroid gland. Insular carcinoma refers to a distinct pattern of poorly differentiated thyroid carcinoma in which the tumor cells are arranged in discrete nests separated by fibrous stroma (nests or insulae, meaning islands) (Fig.
2004. Thyroid nodule shape and prediction of malignancy. Thyroid 14:953–958. Baloch, Z, P Carayon, B Conte-Devolx, LM Demers, U Feldt-Rasmussen, JF Henry, VA LiVosli, P Niccoli-Sire, R John, J Ruf, PP Smyth, CA Spencer, and JR Stockigt. 2003. Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease. Thyroid 13:3– 126. Belfiore, A, GL La Rosa, GA LaPorta, D Giuffrida, G Milazzo, L Lupo, C Regalbuto, and R Vigneri. 1992. Cancer risk in patients with cold thyroid nodules: relevance of iodine intake, sex, age and multinodularity.
Minimally invasive follicular and H¨urthle cell carcinomas). DIFFERENTIATED THYROID CANCER The first major subdivision of follicular tumors is based on the degree of tumor differentiation. The term “differentiated thyroid cancer (DTC)” describes all well differentiated thyroid cancers of follicular cell origin. The two major subgroups of DTC are papillary carcinoma and follicular carcinoma. The architectural and cytologic features of the tumor distinguish papillary from follicular carcinoma. Papillary Thyroid Carcinoma The distinguishing feature of a papillary carcinoma is malignant cytologic (nuclear) changes.