By Prof. Dr. Wolfgang Leistenschneider, Prof. Dr. Reinhard Nagel (auth.)
Diagnostic and exfoliative cytology has this present day accomplished a standing that few can have envisaged two decades in the past. whereas exfoliative cytology has lengthy been hired in gynecological prognosis, new and profitable spheres have now constructed during which cytological analysis performs an enormous function. Exfoliative cytology, for instance, is commonly hired as an relief within the non-stop review of urinary tract tumors, and aspiration cytology within the analysis of thyroid dis eases. This has given upward push to a transforming into call for for pathologists skilled in cytological prognosis. besides the fact that, clinicians with an curiosity in morphology have been frequently the 1st to undertake those basic and secure tools, being certainly attracted via the opportunity to prevent engaging in biopsy, which, within the final research, is not anything lower than a surgical treatment. during this Atlas of Prostatic Cytology Leistenschneider and Nagel expertly display what will be completed whilst clinicians expert in morphology take an curiosity in cytological tools. not just have they got direct touch with the sufferer, yet in addition they make the most of instantly being capable of investigate the result of their diagnostic systems through studying the specimen received. From the technical viewpoint aspiration biopsy of the prostate is under no circumstances an easy process and the problems concerned would appear to were underestimated within the preliminary part of enthusiastic acclaim. for that reason it's been common for clinicians and pathologists to be upset by means of the excessive price of unsatisfactory samples bought through this method.
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Extra info for Atlas of Prostatic Cytology: Techniques and Diagnosis
47b. Same sheet at higher magnifica- tion: the exceedingly thick nuclear membranes are clearly seen. Loose chromatin structure; typical coffee-bean shape of the nuclei in places. x 630 Fig. 48. Sheet of rectal mucosal cells with- out the typical cytoplasmic vacuolation but with the classical nuclear characteristics. x 630 57 Fig. 49. ) and a loose chromatin structure. x 630 Fig. 50. Large sheet of rectal mucosal cells with a transected glandular duct displaying the typical rosette appearance. Nuclei basally situated; cytoplasm of the goblet cells elongated and extensive.
Ing been replaced by the diagnosis 'prostatic carcinoma' in conjunction with the cytological grade of differentiation (G I-G III) (see Chap. 7). 1 Papanicolaou I (Normal Findings) The designation' Pap I' corresponds to a cytologically normal aspirate without any appreciable degree of atypia. 2 Atypia (Papanicolaou II-IV (Table 6) Table 5. Cytological classification (PAPANICOLAOU 1954) I II III IV V Absence of atypical or abnormal cells Atypia, but without evidence of malignancy Suggestive of, but not conclusive for, malignancy Strongly suggestive of malignancy Conclusive signs of malignancy Although Papanicolaou's classification was originally intended for gynecological cytology, it can be adopted as it stands for the classification of prostatic aspirates.
Small, round to oval nuclei with clearly defined nuclear membrane. x400 56 Fig. 47b. Same sheet at higher magnifica- tion: the exceedingly thick nuclear membranes are clearly seen. Loose chromatin structure; typical coffee-bean shape of the nuclei in places. x 630 Fig. 48. Sheet of rectal mucosal cells with- out the typical cytoplasmic vacuolation but with the classical nuclear characteristics. x 630 57 Fig. 49. ) and a loose chromatin structure. x 630 Fig. 50. Large sheet of rectal mucosal cells with a transected glandular duct displaying the typical rosette appearance.