By Dana Dabelea, Georgeanna J. Klingensmith
As the prevalence of youth weight problems maintains to dramatically bring up, the emergence of kind 2 and the expanding occurrence of variety 1 diabetes in youngsters display that early life diabetes, like grownup onset diabetes, is a posh and heterogeneous providing new hindrances to the training clinician. Epidemiology of Pediatric and Adolescent Diabetes is the 1st resource out there to handle this serious paradigm shift and provide insights and suggestions as to how clinicians can larger take care of this turning out to be sufferer population.
Epidemiology of Pediatric and Adolescent Diabetes :
- is the 1st ebook committed in particular to the epidemiology of diabetes in childrens and adolescents
- examines the superiority and scientific manifestations of either sort 1 and kind 2 diabetes in young children and adolescents
- reviews medical trials and results, danger components, problems, and interventions
- includes functional discussions bearing on environmental and behavioral possibility elements, genetics, screening, remedy and prevention, and the way they relate to the kind 1 and a pair of diabetes in adolescents
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Additional info for Epidemiology of Pediatric and Adolescent Diabetes
Example text
N Engl J Med 1990; 323 (17):1167–1172. 10. Srikanta S, Ganda OP, Eisenbarth GS, et al. Islet-cell antibodies and beta-cell function in monozygotic triplets and twins initially discordant for Type I diabetes mellitus. N Engl J Med 1983; 308(6):322–325. 11. Pihoker C, Gilliam LK, Hampe CS, et al. Autoantibodies in diabetes. Diabetes 2005; 54 (suppl 2):S52–S61. 12. Graham J, Hagopian WA, Kockum I, et al. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes.
TWIN STUDIES The genetic liability for diabetes has been investigated by comparing concordance rates for diabetes in monozygotic (identical) twins versus dizygotic twins. In a study of 187 initially discordant monozygotic twins in Great Britain and the United States, the nondiabetic monozygotic twin of a proband diagnosed with diabetes prior to six years of age had a 60% risk for developing diabetes within 40 years of follow-up (23).
2. Master Series: Etienne Lancereaux. Diabetologia 2005; 48(11). 3. Gale EA. The discovery of type 1 diabetes. Diabetes 2001; 50(2):217–226. 4. World Health Organization. Diabetes Mellitus: Report of a WHO Expert Committee. World Health Organization Technical Support Series 1965(310). 5. National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1979; 28(12):1039–1057. 6. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus.