Childhood Epilepsy: Management from Diagnosis to Remission by Richard Appleton, Peter Camfield

By Richard Appleton, Peter Camfield

Sixty percentage of the epilepsies commence in early life, and lots of the clinically major and sometimes life-changing features of the affliction happen at the moment. youth epilepsy is often a posh sickness, hard built-in clinical, academic and group providers. Its remedy encompasses acute and incapacity medication. the numerous kinds or syndromes of formative years epilepsy current either diagnostic and administration demanding situations. even if many kids with epilepsy could be stated expert devices, the bulk will firstly current to paediatricians and paediatric neurologists. This booklet presents a pragmatic, problem-oriented handbook to assist clinicians with prognosis, review and administration. This booklet addresses epilepsy as an evolving affliction from presentation, via energetic illness and at last to both spontaneous remission or a protracted lifelong situation. established at the kid's age at presentation, formative years Epilepsy deals a pragmatic review for paediatricians, paediatric neurologists and first care practitioners who deal with childrens with epilepsy of their day-by-day perform.

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Childhood Epilepsy: Management from Diagnosis to Remission

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Extra resources for Childhood Epilepsy: Management from Diagnosis to Remission

Example text

Brain 2010; 133: 655–70. 6. Basura GJ, Hagland SP, Wiltse AM, Gospe SM Jr. Clinical features and the management of pyridoxine-dependent and pyridoxine-responsive seizures: review of 63 North American cases submitted to a patient registry. Eur J Pediatr 2009; 168: 697–704. 7. Kellaway P, Hrachovy RA, Frost JD Jr, Zion T. Precise characterization and quantification of infantile spasms. Ann Neurol 1979; 6: 214–18. 8. Dravet C, Bureau M, Oguni H, Fukuyama Y, Cokar O. Severe myoclonic epilepsy in infancy: Dravet syndrome.

The prognosis is less certain than for the other idiopathic focal epilepsies. Approximately 60% will remit within four years, however some continue to have seizures long term. ’ Implicit in the term is the concept that the encephalopathy is the consequence of the epilepsy, resulting from very frequent clinical seizures, continuous or semicontinuous paroxysmal EEG activity (spike and wave), or both. Epileptic encephalopathies presenting in childhood  myoclonic–astatic epilepsy (MAE)  Lennox–Gastaut syndrome  Dravet syndrome (seizure onset is in infancy but epileptic encephalopathy develops later)  continuous spike-wave of slow-sleep (CSWSS)  Rassmussen syndrome  severe symptomatic epilepsies – including those caused by neuro-degenerative and/or metabolic disorders Epilepsy with myoclonic–astatic seizures (also known as Doose syndrome) is characterized by the occurrence of myoclonic–astatic seizures together with other seizure types.

Sheth RD, Bodensteiner JB. Effective utilization of home-video recordings for the evaluation of paroxysmal events in pediatrics. Clin Pediatr 1994; 33: 578–82. 3. Berrington de Gonza´lez A, Mahesh M, Kim KP, et al. Projected cancer risks from computed tomographic scans performed in the United States in 2007. Arch Intern Med 2009; 169: 2071–7. 4. Wolf B. Clinical issues and frequent questions about biotinidase deficiency. Mol Genet Metab 2010; 100: 6–13. 5. Leen WG, Klepper J, Verbeek MM, et al.

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