Caffeine for the Sustainment of Mental Task Performance: by Committee on Military Nutrition Research, Food and Nutrition

By Committee on Military Nutrition Research, Food and Nutrition Board, Institute of Medicine

This file from the Committee on army foodstuff examine stories the background of caffeine utilization, the metabolism of caffeine, and its physiological results. the results of caffeine on actual functionality, cognitive functionality and application, and relief of sleep deprivation impairments are mentioned in mild of contemporary medical literature. The effect of caffeine intake on numerous points of health and wellbeing, together with heart problems, copy, bone mineral density, and fluid homeostasis are reviewed. The behavioral results of caffeine also are mentioned, together with the impact of caffeine on response to emphasize, withdrawal results, and hazardous results of excessive intakes. The quantities of caffeine discovered to reinforce vigilance and response time continuously are reviewed and suggestions are made with appreciate to quantities of caffeine acceptable for protecting alertness of army body of workers in the course of box operations. strategies also are supplied at the desire for acceptable labeling of caffeine-containing supplementations, and schooling of army body of workers at the use of those vitamins. a short assessment of a few possible choices to caffeine can also be supplied.

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Extra resources for Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations

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Please use the print version of this publication as the authoritative version for attribution. PHARMACOLOGY OF CAFFEINE 26 doses up to 10 g has caused convulsions and vomiting with complete recovery in 6 hours (Dreisbach, 1974). , 1990), including restlessness, nervousness, and irritability, and progressing to delirium, emesis, neuromuscular tremors, and convulsions. Other symptoms included tachycardia and increased respiration. FIGURE 2–1 Chemical structure of methylxanthines. , 1997). When it is consumed in beverages (most commonly coffee, tea, or soft drinks) caffeine is absorbed rapidly from the gastrointestinal tract and distributed throughout body water.

Specifically, the military provided the following information and questions for the committee’s response. A specific transition opportunity could take the following form: a “HOOAH” food bar (a nutrient-dense energy bar developed by the Army) containing 600 mg of caffeine, scored in 150-mg increments, with labeling that provides specific guidance for use of up to one food bar (600 mg) to offset deficits in cognitive About this PDF file: This new digital representation of the original work has been recomposed from XML files created from the original paper book, not from the original typesetting files.

The fact that the human body converts 70–80 percent of caffeine into paraxanthine with no apparent toxic effects following caffeine doses of 300– 500 mg/day suggests that paraxanthine’s toxicological potency is low. Formation of paraxanthine and its excretion in the urine appears to be the major pathway for caffeine metabolism (Stavric, 1988). Hetzler et al. (1990) demonstrated that lipolytic effects of caffeine may be due to the action of paraxanthine rather than caffeine itself. Increasing concentration of plasma-free fatty acids following intravenous administration of caffeine was negatively correlated to plasma caffeine concentrations, and highly positively correlated to plasma paraxanthine concentrations.

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