By Tuula T. Teeri, Birte Svensson, Harry J. Gilbert
(Royal Society of Chemistry) Royal Institute of expertise, Stockholm, Sweden. The lawsuits of the 4th Carbohydrate Bioengineering assembly hung on June 10-13, 2001, on the Royal Institute of know-how, Stockholm, Sweden. For researchers and practitioners in drugs, chemical, nutrients, and pharmaceutical components.
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Hoffmann-Sommergruber, 0. Scheiner, D. Kraft, M. -J. Rheinberger, and C. Ebner, J. Exp. , 1996, 183, 599. 32. R. Valenta, S. Vrtala, T. Ball, S. Laffer, P. Steinberger, and D. Kraft, ACI News, 1994, 6/6, 165. STRUCTURE AND FUNCTION OF CLASS I c~~,~-MANNOSIDASES INVOLVED EN GLYCOPROTEIN BIOSYNTHESIS A. Herscovics', F. Lipari', B. A. Romero', F. Vallee2, P. Yip2 and P. L. Howell2 'McGill Cancer Centre, McGill University, Montr6a1, Canada *TheHospital for Sick Children, Toronto, Canada. 1 INTRODUCTION Class I al,2-mannosidases (glycosylhydrolase family 47) are a family of proteins that play an important role in the early stages of glycoprotein synthesis (1-3).
Chem. ,1996, 118,6804. 16. A. M. W. H. Thunnissen, H. J. Rozenboom, K. H. Kalk and B. W. Dijkstra, Biochemistry, 1995,34,12729. 17. K. E. Luker, J. L. Collier, E. W. Kolodziej, G. R. Marshall and W. E. Goldman, Proc. Natl. Acad. Sci. USA, 1993,90, 12652. 18. A. J. Clarke and C. Dupont, Can. J. , 1992,38, 85. STRUCTURAL STUDIES OF THE RETAINING GALACTOSYLTRANFERASE LGTC FROM NEISSERIA MENINGITIDIS K. Persson', H. Ly2,M. Dickelmann3,W. Wakarchuk3, S. Withers2and N. , Canada, V6T 1Z1, 31nstitute for Biological Sciences, National Research Council, Ottawa, Canada, K1A OR6 1 INTRODUCTION Bacterial pathogens such as Neisseria, Helicobacter, Campylobacter and many more express lipooligosaccharides (LOS) on their cell surface that mimic human cell surface glycolipids.
Howell, J. Biol. ,2000,275,41287-41298. Acknowledgments This work was supported by grants from NIH (GM3 1265), NSERC and CIHR STRUCTURE AND FUNCTION OF LYTIC TRANSGLYCOSYLASES FROM Pseudomonas aeruginosa N. T. Blackburn and A. J. Clarke Department of Microbiology University of Guelph Guelph, Ontario N 1G 2W 1 Canada 1 INTRODUCTION As with plants, algae, and fwngi, bacteria produce a rigid polymer of p,1-4 linked glycosides that comprises the bulk of their cell walls. These polymers withstand the internal turgor pressure of the cytoplasm thereby maintaining the integrity of the cytoplasmic membranes.